The painkiller Ibuprofen can damage the fertility of men. Those who take the drug in high doses over a longer period of time risk its reproductive performance and other health problems, such as muscle wasting or erectile dysfunction. This is the conclusion of an international team of scientists in a recent study.
Ibuprofen interferes with the production of testosterone The analgesic is said to alter hormone production in the male gonads, researchers say in the journal Proceedings of the National Academy of Sciences (PNAS).
Among those taking the ibuprofen drug, the hormone level of sperm production increased. This increase has a negative effect on the sex hormone testosterone, which can lead to decreased fertility. Up to six weeks, 14 men between the ages of 18 and 35 took the analgesic for the study, a daily dose of 600 milligrams twice a day. A comparison group of 17 men got placebos.
The researchers found that the drug interfered with the production of sex hormone in healthy, young men. They had a physical condition that was expected of smokers or older men.
A permanent fertility disorder is feared The doctors in the study fear that this disorder could also develop permanently into fertility, which was only mild and transient in the subjects. “Our immediate concern is the fertility of men taking the drug over a long period of time,” said David Møbjerg Kristensen of the University of Copenhagen on the Guardian.
Ibuprofen is an effective analgesic, according to the author of the study. However, too many people still would not think that this is a real drug.